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Treatment cost varies depending on how complex the problem is and which tooth is affected. Molars are more difficult to treat; the fee is usually more. Most dental insurance policies provide some coverage for endodontic treatment.

Generally, endodontic treatment and restoration of the natural tooth are less expensive than the alternative of having the tooth extracted and replaced with an implant or bridge to restore chewing function and prevent adjacent teeth from shifting. These combined procedures tend to cost more than endodontic treatment and appropriate restoration.